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Integrating Single-cell and Bulk RNA Sequencing Data Unveils Antigen Presentation and Process-related CAFs and Establishes a Predictive Signature in Prostate Cancer

2023-08-10

Abstract excerpt

<title>Abstract</title> <p>Background Cancer-associated fibroblasts (CAFs) are heterogeneous and can influence the progression of prostate cancer in multiple ways. However, their capacity to present and process antigens in PRAD has not been investigated. In this study, antigen presentation and process-related CAFs (APPCAFs) were identified using bioinformatics, and the clinical implications of APPCAFs-related si...

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Literature Corpus work
29f6dc4b-7d4c-53f5-a8f2-9d3ea3f2928a
DOI
10.21203/rs.3.rs-3224548/v1
Open publication

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Integrating Single-cell and Bulk RNA Sequencing Data Unveils Antigen Presentation and Process-related CAFs and Establishes a Predictive Signature in Prostate CancerDOI 10.21203/rs.3.rs-3224548/v1
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