Article

Revealing architectural order with quantitative label-free imaging and deep learning

2019-05-09

Abstract excerpt

Quantitative imaging of biological architecture with fluorescent labels is not as scalable as genomic or proteomic measurements. Here, we combine quantitative label-free imaging and deep neural networks for scalable analysis of complex structures. We reconstruct quantitative three-dimensional density, anisotropy, and orientation in live cells and tissue slices from polarization- and depth-resolved images. We repor...

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Identifiers and source

Literature Corpus work: 29e55985-f680-56b5-990f-2a75bde9a723
DOI: 10.1101/631101

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