Article
miRCoop: Identifying Cooperating miRNAs via Kernel Based Interaction Tests
2019-09-14
Abstract excerpt
Although miRNAs can cause widespread changes in expression programs, single miRNAs typically induce mild repression on their targets. Cooperativity is reported as one strategy to overcome this constraint. Expanding the catalog of synergistic miRNAs is critical for understanding gene regulation and for developing miRNA-based therapeutics. In this study, we develop miRCoop to identify synergistic miRNA pairs that ha...
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Identifiers and source
- Literature Corpus work
- 29e34b2b-4dd4-5107-9cf1-5f8cd4c4b80c
- DOI
- 10.1101/769307