Article
In silico prediction of potential miRNA-disease association using an integrative bioinformatics approach based on kernel fusion.
Journal of cellular and molecular medicine - 1 Jan 2020
Guan Na-Na, Wang Chun-Chun, Zhang Li, Huang Li, Li Jian-Qiang, Piao Xue
Abstract excerpt
Accumulating experimental evidence has demonstrated that microRNAs (miRNAs) have a huge impact on numerous critical biological processes and they are associated with different complex human diseases. Nevertheless, the task to predict potential miRNAs related to diseases remains difficult. In this paper, we developed a Kernel Fusion-based Regularized Least Squares for MiRNA-Disease Association prediction model...
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