Article

Paracoccin overexpression in <i>Paracoccidioides brasiliensis</i> reveals the influence of chitin hydrolysis on fungal virulence and host immune response

2019-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Paracoccidioides brasiliensis and P. lutzii , etiological agents of paracoccidioidomycosis (PCM), develop as mycelia at 25-30 °C and as yeast at 35-37 °C. Only a few Paracoccidioides spp. proteins are well characterized. Thus, we studied paracoccin (PCN) from P. brasiliensis , its role in the fungus biology, and its relationship with the host innate immune cells. Cloning and heterologous expr...

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Literature Corpus work: 29bd8cde-2cb0-53eb-b6e6-9dbe67282e4a
DOI: 10.1101/515056

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