Article

Viral evolution during primary infection in immunocompromised hosts

2025-09-04

Abstract excerpt

The immune response to viral infection is a delicate balance. By perturbing this balance, immunodeficiencies are expected to influence within-host viral evolution. Indeed, the presence of immunocompromised hosts has been argued to be a source of novel viral variants in some infectious diseases, including SARS-CoV-2. However, these arguments rest upon between-host models and so the role of immunodeficiencies on wit...

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Literature Corpus work: 283c041b-34fe-535e-ad0f-e1568d9a7f1d
DOI: 10.1101/2025.09.01.673077

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