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Article

Characterisation of oestrogenic activity of ginsenosides in MCF-7 cells using a customised DNA microarray

2009-03-01

Abstract excerpt

We studied oestrogenic activity of components of ginseng: ginsenosides F1, Rb1, Rg1 and Rh1. These ginsenosides dose-dependently stimulated the proliferation and oestrogen-responsive luciferase activity of human breast cancer MCF-7 cells, with a maximal level at 100μM. Both proliferation and luciferase activities induced by ginsenosides were blocked by ICI 182,780, an oestrogen receptor antagonist. We further exam...

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Literature Corpus work
27f603d3-4310-5cb3-be1f-51802a6cea91
DOI
10.1016/j.foodchem.2008.07.100
Open publication

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Characterisation of oestrogenic activity of ginsenosides in MCF-7 cells using a customised DNA microarrayDOI 10.1016/j.foodchem.2008.07.100
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