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Resveratrol induces downregulation of DNA repair genes in MCF-7 human breast cancer cells

25 May 2012

Abstract excerpt

To gain insights into the antitumor mechanisms of resveratrol (RES), we carried out a DNA microarray analysis in the breast cancer cell line MCF-7 to study the global gene expression profile induced by RES treatment. The mRNA expression level of 19 734 well-characterized human genes from MCF-7 cells was determined using Affymetrix microarrays under two different RES treatments: 150 μmol/l (IC(50)) and 250 μmol/l...

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PMID: 22644231
DOI: 10.1097/cej.0b013e328353edcb

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