Article

miR-450a-5p eliminats MGO-induced insulin resistance via targeting CREB

2019-07-30

Abstract excerpt

<title>Abstract</title> <p>Background miR-450a-5p was involved in fat formation, but its role in insulin resistance remains unclear. This study further investigated the effects of miR-450a-5p in endothelial cells, with the aim of finding a potential target for diabetes mellitus. Methods Human umbilical vein endothelial cells (HUVECs) were severally treated with low-glucose, high-glucose, methylglyoxal (MGO), a...

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Literature Corpus work: 27aed292-e793-599a-8704-76c58f0918a7
DOI: 10.21203/rs.2.12119/v1

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