Article

Comparative Analysis Of Orthologous Mast Cell Chymases Active Sites Using Bioinformatics Tools

2021-08-23

Abstract excerpt

Mast cells, neutrophils, basophils, natural killer cells, and cytotoxic T cells are among the hematopoietic cell lines originating from immune cells. The importance of mammalian mast cells in innate immunity has piqued the scientific community's interest. cytoplasmic granules of mast cells. Histamine, proteoglycans, proteins, and cytokines are examples of compounds (mediators) that produce mast cell cytoplasmic gr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 27aca604-3015-5780-95a8-6d7b20927c63
DOI: 10.21203/rs.3.rs-827996/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative Analysis Of Orthologous Mast Cell Chymases Active Sites Using Bioinformatics ToolsDOI 10.21203/rs.3.rs-827996/v1Read

Analysis of the mast cell expressed carboxypeptidase A3 and its structural and evolutionary relationship to other vertebrate carboxypeptidasesSemantic proximity Read

Mast cell-restricted tryptases: structure and function in inflammation and pathogen defense.Semantic proximity Read

Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution.Semantic proximity Read

The extended cleavage specificity of the rodent β-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymaseSemantic proximity Read

The transcriptional program, functional heterogeneity, and clinical targeting of mast cellsSemantic proximity Read

Diagnosis, Classification and Management of Mast Cell Activation Syndromes (MCAS) in the Era of Personalized Medicine.Semantic proximity Read

The Human Mast Cell Chymase Gene (CMA1): Mapping to the Cathepsin G/Granzyme Gene Cluster and Lineage-Restricted ExpressionSemantic proximity Read

Carboxypeptidase A3-A Key Component of the Protease Phenotype of Mast Cells.Semantic proximity Read

Mast cell tryptases in allergic inflammation and immediate hypersensitivity.Semantic proximity Read

Mast cells: Versatile regulators of inflammation, tissue remodeling, host defense and homeostasisSemantic proximity Read

Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution.Semantic proximity Read

The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profileSemantic proximity Read