Article

Multi-omic modeling of antidepressant response implicates dynamic immune and inflammatory changes in individuals who respond to treatment

2022-10-08

Abstract excerpt

Major depressive disorder (MDD) is a leading cause of disability worldwide, and is commonly treated with antidepressant drugs (AD). Although effective, many patients fail to respond to AD treatment, and accordingly identifying factors that can predict AD response would greatly improve treatment outcomes. In this study, we developed a machine learning tool to integrate multi-omic datasets (gene expression, DNA meth...

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Literature Corpus work: 272121cf-29ce-58f5-8098-1011f4b6ad17
DOI: 10.1101/2022.10.07.511374

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