Article

Increasing Signal Intensity of Fluorescent Oligo-Labeled Antibodies to Enable Combination Multiplexing

2023-07-06

Abstract excerpt

Full-spectrum flow cytometry has increased antibody-based multiplexing, yet further increases remain potentially impactful. We recently proposed how fluorescence Multiplexing using Spectral Imaging and Combinatorics (MuSIC) could do so using tandem dyes and an oligo-based antibody labeling method. In this work, we found that such labeled antibodies had significantly lower signal intensity than conventionally-label...

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Literature Corpus work: 26c2a09f-df1e-5ea3-8a65-dc95468a8d57
DOI: 10.1101/2023.07.06.547965

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