Article

Spatiotemporal 7q11.23 Protein Network Implicates the GTF2I-PRKDC-DDR Pathway During Early-Fetal Brain Development in Psychiatric Diseases

2020-10-26

Abstract excerpt

<h4>Background: </h4> Recurrent deletions and duplications of chromosome 7q11.23 copy number variants (CNVs) are associated with several psychiatric disorders. Previous works showed GTF2I associated with Williams-Beuren syndrome, but pathways affected by GTF2I are poorly defined. Although phenotypic abnormalities have been observed in patients and animal models, the targeted human brain regions, developmental stag...

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Literature Corpus work: 25e50fff-d25a-5be6-8ebb-057fc0bd7dee
DOI: 10.21203/rs.3.rs-93461/v1

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