Article

Porcine parvovirus infection induces necroptosis of porcine placental trophoblast cells via a ZBP1-mediated pathway

2024-05-22

Abstract excerpt

<title>Abstract</title> <p>Porcine parvovirus (PPV) infection induces germ cell death, leading to reproductive disorders in first-pregnant sows. Porcine placental trophoblast cells (PTCs) are the major target of PPV, and we have previously found that PPV infection leads to the death of PTCs by a non-apoptotic process, which may be related to PPV pathogenicity. The Z-nucleic acid-binding protein 1 (ZBP1) is often...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25678332-8736-5456-a5ab-e855067e9df3
DOI: 10.21203/rs.3.rs-4306585/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Porcine parvovirus infection induces necroptosis of porcine placental trophoblast cells via a ZBP1-mediated pathwayDOI 10.21203/rs.3.rs-4306585/v1Read

Autophagy Promotes Porcine Parvovirus Replication and Induces Non-Apoptotic Cell Death in Porcine Placental TrophoblastsSemantic proximity Read

ASFV infection induces macrophage necroptosis and releases proinflammatory cytokine by ZBP1-RIPK3-MLKL necrosome activationSemantic proximity Read

ZBP1 inhibits the replication of Senecavirus A by enhancing NF-κB signaling pathway mediated antiviral response in porcine alveolar macrophage 3D4/21 cellsSemantic proximity Read

Unveiling the Role of Protein Kinase C θ in Porcine Epidemic Diarrhea Virus Replication: Insights from Genome-Wide CRISPR/Cas9 Library ScreeningSemantic proximity Read

Porcine parvovirus triggers autophagy through the AMPK/Raptor/mTOR pathway to promote viral replication in porcine placental trophoblastsSemantic proximity Read

Necroptosis in development and diseases.Semantic proximity Read

Characterization of a Previously Unidentified Viral Protein in Porcine Circovirus Type 2-Infected Cells and Its Role in Virus-Induced ApoptosisSemantic proximity Read

Porcine Epidemic Diarrhea Virus Induces Vero Cell Apoptosis via the p53-PUMA Signaling PathwaySemantic proximity Read

Interference of pseudorabies virus infection on functions of porcine granulosa cells via apoptosis modulated by MAPK signaling pathwaysSemantic proximity Read

Human Cytomegalovirus Inhibits the Proliferation and Invasion of Extravillous Cytotrophoblasts Via Hippo-YAP PathwaySemantic proximity Read

Parvovirus Infection-Induced Cell Death and Cell Cycle ArrestSemantic proximity Read

Betanodavirus: Mitochondrial disruption and necrotic cell deathSemantic proximity Read