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Article

Phylogenetic barriers to horizontal transfer of antimicrobial peptide resistance genes in the human gut microbiota

2018-08-07

Abstract excerpt

The human gut microbiota has adapted to the presence of antimicrobial peptides (AMPs) that are ancient components of immune defence. Despite important medical relevance, it has remained unclear whether AMP resistance genes in the gut microbiome are available for genetic exchange between bacterial species. Here we show that AMP- and antibiotic-resistance genes differ in their mobilization patterns and functional co...

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Identifiers and source

Literature Corpus work
25049275-8e89-50f9-87d0-2ea10489795f
DOI
10.1101/385831
Open publication

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