Article

Generalizing population RT-qPCR cycle threshold values-informed estimation of epidemiological dynamics: Impact of surveillance practices and pathogen variability

2025-05-22

Abstract excerpt

Population-level viral load distributions, measured by RT-qPCR or qPCR cycle threshold (Ct) values from surveillance testing, can be used to estimate the time-varying reproductive number ( R t ) in real-time during COVID-19 outbreaks. However, it remains unclear whether this approach can be broadly applied to other pathogens, sources of virologic test data, or surveillance strategies beyond those used during the p...

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Literature Corpus work: 2442c8ea-6c4d-5d7f-81e5-2c1995c8eb79
DOI: 10.1101/2025.05.22.25328079

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