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Article

In vivo kinetics of SARS-CoV-2 infection and its relationship with a person’s infectiousness

2 Dec 2021

Abstract excerpt

The within-host viral kinetics of SARS-CoV-2 infection and how they relate to a person's infectiousness are not well understood. This limits our ability to quantify the impact of interventions on viral transmission. Here, we develop viral dynamic models of SARS-CoV-2 infection and fit them to data to estimate key within-host parameters such as the infected cell half-life and the within-host reproductive number....

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PMID: 34857628
DOI: 10.1073/pnas.2111477118

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