Article

FYCO1 improves postischemic cardiac remodeling via enhanced autophagic flux and attenuation of proinflammatory signaling

2026-03-18

Abstract excerpt

Acute myocardial infarction (MI) is associated with severe metabolic and oxidative stress that triggers cardiomyocyte death, pro-inflammatory signaling and progressive structural remodeling frequently culminating in heart failure. Although significant advances in reperfusion therapy improved acute survival in patients, therapeutic strategies that directly target intracellular processes in response to injury remain...

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Literature Corpus work: 240b2836-2734-5dee-b7c7-fb3128a8858f
DOI: 10.64898/2026.03.17.712297

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