Article

The induction of SARS-CoV-2-specific CD8+ T cell immunity uncouples with the viral spread in K18-hACE2 infected mice

2023-05-25

Abstract excerpt

Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 enters the host by infecting nasal ciliated cells. The virus then spreads toward the oropharyngeal cavity, and, in most severe cases, the pulmonary tissues. The antiviral adaptive response is promptly induced in response to virus detection, with virus-specific T lymphocytes appearing before antiviral antibodies. Both breadth and potency of the antiviral CD...

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Literature Corpus work: 2351b3ae-0d13-53b2-8a86-09273ef41173
DOI: 10.21203/rs.3.rs-2950996/v1

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