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Induction of SARS-CoV-2 N-specific CD8 <sup>+</sup> T cell immunity in lungs by engineered extracellular vesicles associates with strongly impaired viral replication

2023-01-20

Abstract excerpt

Induction of effective immunity in lungs should be a pre-requisite for any vaccine designed to control the severe pathogenic effects generated by respiratory infectious agents. In the case of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection, vaccination is expected to associate with significant inhibition of viral replication in lungs. We recently provided evidence that the generation of endoge...

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Literature Corpus work
1e2b7b92-17ac-5ac1-b5f3-c08db4ddbb20
DOI
10.1101/2023.01.19.524762
Open publication

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Induction of SARS-CoV-2 N-specific CD8 <sup>+</sup> T cell immunity in lungs by engineered extracellular vesicles associates with strongly impaired viral replicationDOI 10.1101/2023.01.19.524762
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