Article

An allelic series reveals the genetic requirement for Adnp in cortical neurogenesis and learning behavior

2026-06-11

Abstract excerpt

Transcriptional regulators and chromatin remodellers are among the most important risk gene categories across the genetic landscape of neurodevelopmental disorders (NDDs). The zinc finger and homeodomain transcription factor ADNP is prominently associated with Helsmoortel-Van der Aa Syndrome (HVDAS), which is characterized by intellectual disability and autism spectrum disorder. Heterozygous frameshifting mutatio...

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Literature Corpus work: 22ccfd7b-ae02-5f86-a1d4-fa569fdc0f99
DOI: 10.64898/2026.06.10.731333

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