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Urine Cellular DNA Point Mutation and Methylation as Potential Biomarkers for the Detection of Urothelial Carcinoma

2021-11-19

Abstract excerpt

<h4>Background: </h4> Previously, our team identified a seven-gene mutation panel in urine sediment to discriminate UBC from benign urological diseases. In the present study, we aimed to validate the panel in an expanded and close to natural population cohort of hematuria. Also, we tried to optimize the panel by incorporating methylation biomarkers. We performed external validation to investigate the robustness an...

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Literature Corpus work
222dfcd9-15e0-532d-827e-e27e3a5f8335
DOI
10.21203/rs.3.rs-1078677/v1
Open publication

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