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Five-year (2017-2022) evolutionary dynamics of human coronavirus HKU1 in southern France with emergence of viruses harboring spike H512R substitution

2024-08-27

Abstract excerpt

<h4>Objectives: </h4> HCoV-HKU1 diversity and evolution was scarcely studied. We performed next-generation sequencing (NGS) and analysis of HCoV-HKU1 genomes over five years. <h4>Methods: </h4> NGS used Illumina technology on NovaSeq 6000 following whole genome PCR amplification by a in-house set of primers designed using Gemi and PrimalScheme. Genome assembly and analyses used CLC Genomics, Mafft, BioEdit, Nexts...

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Literature Corpus work
21bfd25e-a63a-57fe-a344-b96ba55eff46
DOI
10.22541/au.172473141.14580969/v1
Open publication

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