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Article

Five-Year (2017-2022) Evolutionary Dynamics of Human Coronavirus OC43 in Southern France Based on Whole Genome Next-Generation Sequencing.

Journal of medical virology - 1 Dec 2025

Houmadi Hikmat, Boschi Céline, Lefebvre Marine, Le Targa Lorlane, Py Justine, Lagier Jean-Christophe, Lesage Lucile, Fantini Jacques, Morand Aurélie, La Scola Bernard, Colson Philippe

Abstract excerpt

HCoV-OC43 genomes and their evolution are scarcely studied worldwide and in France, with only 361 genomes available as of October 2023. Here, an in-house PCR amplification system was implemented to obtain retrospectively by next-generation sequencing, then analyze HCoV-OC43 genomes for infections diagnosed with this virus in southern France between February 2017 and October 2022. Multiplex PCR amplification using...

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PMID: 41332365
DOI: 10.1002/jmv.70726
PMCID: PMC12673430

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