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Cross-species Study of Canine and Human Peripheral Nerve Sheath Tumors: Clinical and Molecular Perspectives

2026-07-29

Abstract excerpt

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas. An obstacle to treating MPNSTs is a lack of effective systemic therapies. Although over 70% of human MPNSTs have lost or inactivated the epigenome regulator polycomb repressive complex 2 ( PRC2 ), its activity and contribution to canine PNST progression remain unclear. This study compared canine peripheral nerve sheath tumors (PNSTs) and h...

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Literature Corpus work
21b96bb4-384a-5d6f-b9dd-2e4912978b84
DOI
10.64898/2026.07.28.740600
Open publication

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Cross-species Study of Canine and Human Peripheral Nerve Sheath Tumors: Clinical and Molecular PerspectivesDOI 10.64898/2026.07.28.740600
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