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ARPC1A correlates with poor prognosis in prostate cancer and is up-regulated by glutamine metabolism to promote tumor cell migration, invasion and cytoskeletal changes

22 Feb 2023

Abstract excerpt

OBJECTIVE: This study aimed to identify potential biomarkers for prostate cancer (PCa) progression and metastasis, and to discern their biological functions. METHODS: Bioinformatics methods were used to screen for hub genes. The expression level of key hub genes in PCa was determined and their prognostic significance was examined. A series of functional assays were performed to investigate the function of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36814338
DOI: 10.1186/s13578-023-00985-w

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