Article

Deferiprone Related Bone Disease May Be Related to Associated Gilbert Syndrome

2022-06-14

Abstract excerpt

Gilbert Syndrome, is a benign condition characterized by persistent indirect hyperbilirubinemia due to reduced UDP-glucuronyltransferase enzyme activity. Its coexistence with other clinical disorders has important clinical and pharmacological implications. GS is known to coexist with many hemolytic conditions and may lead to diagnostic difficulty and also increased incidence of gallstones. UGT1A1 gene has been sho...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2105f16a-0d0a-5269-856c-3453c6a16219
DOI: 10.20944/preprints202206.0203.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Deferiprone Related Bone Disease May Be Related to Associated Gilbert SyndromeDOI 10.20944/preprints202206.0203.v1Read

UGT1A6 variants and deferiprone-induced ADRs: a complication-specific analysis in Iranian thalassemia patients.Semantic proximity Read

Pharmacogenetic Study of Deferasirox, an Iron Chelating AgentSemantic proximity Read

Three most common nonsynonymous UGT1A6*2 polymorphisms (Thr181Ala, Arg184Ser and Ser7Ala) and therapeutic response to deferiprone in β-thalassemia major patients.Semantic proximity Read

FEATURES OF GILBERT'S SYNDROME IN PATIENTS WITH DIFFERENT GENOTYPES UGT1AI.Semantic proximity Read

Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants.Semantic proximity Read

UGT1A6 genotype-related pharmacokinetics of deferiprone (L1) in healthy volunteers.Semantic proximity Read

Brentuximab vedotin related neuropathy in a patient with Gilbert syndrome: Do mutations of UGT1A1 gene affect brentuximab toxicity?Semantic proximity Read

The relationship between UGT1A1 gene & various diseases and prevention strategiesSemantic proximity Read