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An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces sterile immunity and prevents transmission of SARS-CoV-2 between cats

2021-04-01

Abstract excerpt

Early in the global SARS-CoV-2 pandemic concerns were raised regarding infection of other animal hosts and whether these could play a significant role in the viral epidemiology. Infection of animals could be detrimental by causing clinical disease but also of concern if they become a viral reservoir allowing further mutations, plus having the potential to infect other animals or humans. The first reported animals...

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Identifiers and source

Literature Corpus work
20e50085-5227-5d14-a833-e9c699cabdbe
DOI
10.1101/2021.04.01.436305
Open publication

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An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces sterile immunity and prevents transmission of SARS-CoV-2 between catsDOI 10.1101/2021.04.01.436305
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