Article
Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
2021-12-01
Abstract excerpt
The thyroid gland captures iodide in order to synthesize hormones that act on almost all tissues and are essential for normal growth and metabolism. Low plasma levels of thyroid hormones lead to hypothyroidism, which is one of the most common disorder in humans and is not always satisfactorily treated by lifelong hormone replacement. Therefore, in addition to the lack of in vitro tractable models to study human t...
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Identifiers and source
- Literature Corpus work
- 205e7a1c-e27b-54f3-8dd8-12709a2012e6
- DOI
- 10.1101/2021.12.01.470729