Article

A Comprehensive Study of De Novo Mutations on Protein-protein Interaction Interface Provides New Insights in Developmental Delay

2022-08-19

Abstract excerpt

Mutations, especially those at the protein-protein interaction (PPI) interface, have been associated with various diseases. Meanwhile, though de novo mutations (DNMs) have been proven important in neuropsychiatric disorders, such as developmental delay (DD), the relationship between PPI interface DMNs and DD has not been well studied. Here we curated developmental delay DNM datasets from the PsyMuKB database and s...

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Literature Corpus work: 1fd5b138-e552-5e46-8aeb-2b03c29d6854
DOI: 10.20944/preprints202208.0355.v1

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