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Altered ACE2 and interferon landscape in the COVID-19 microenvironment correlate with the anti-PD-1 response in solid tumors

2024-07-23

Abstract excerpt

<title>Abstract</title> <p>Angiotensensin-converting enzyme-2 (ACE2) is a receptor for SARS-CoV-2, allowing the virus to enter cells. Although tumor patients infected by SARS-CoV-2 often have a worse outcome, the expression, function and clinical relevance of ACE2 in tumors has not yet been thoroughly analyzed. In this study, RNA sequencing (RNA-seq) data from tumors, adjacent tissues and whole blood samples of C...

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Literature Corpus work
1f8828b7-d2c2-571d-bb9c-c429113ed51d
DOI
10.21203/rs.3.rs-4619449/v1
Open publication

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Altered ACE2 and interferon landscape in the COVID-19 microenvironment correlate with the anti-PD-1 response in solid tumorsDOI 10.21203/rs.3.rs-4619449/v1
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