Article

Prediction of Micronucleus Assay Outcome using in Vivo Activity Data and Molecular Structure Features

2021-07-21

Abstract excerpt

<title>Abstract</title> <p>In vivo micronucleus assay is the widely used genotoxic test to determine the extent of chromosomal aberrations caused by the chemical compounds in human beings, which plays a significant role in the drug discovery paradigm. To reduce the uncertainties of the in vivo experiments and the expenses, we intended to develop novel machine learning-based tools to predict the toxicity of the co...

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Literature Corpus work: 1f6b4211-be98-5607-baf2-13814e317eec
DOI: 10.21203/rs.3.rs-721125/v1

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