Article

FOXO3a Negatively Regulates miR-155-5p Expression to impact the proliferation and invasion of Renal Cell Carcinoma

2023-03-20

Abstract excerpt

The development of targeted therapy and biotherapy drug resistance is the major barrier in terminal Renal Cell Carcinoma (RCC) therapy. Emerging evidence revealed that FOXO3a could be regulated to suppress RCC. In this study, the regulatory mechanism of FOXO3a on miR-155 and their specific effects in the development of RCC were investigated. We found that FOXO3a was down-regulated in RCC tissues and cell lines, wh...

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Literature Corpus work: 1e31c4b4-dc37-5893-8457-4010b36a557f
DOI: 10.21203/rs.3.rs-2674328/v1

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