Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-375 Suppresses the Tumor Aggressive Phenotypes of Clear Cell Renal Cell Carcinomas through Regulating YWHAZ.

Chinese medical journal - 20 Aug 2018

Zhang Xiang, Xing Nai-Dong, Lai Cheng-Jun, Liu Rui, Jiao Wei, Wang Jue, Song Jie, Xu Zhong-Hua

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are key regulators during tumor initiation and progression. MicroRNA-375 (MiR-375) has been proven to play a tumor-suppressive role in various types of human malignancies; however, its biological role in clear cell renal cell carcinoma (ccRCC) remains unclear. The purpose of this study was to explore the biologic role as well as the underlying mechanism of miR-375 in ccRCC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 Proteins
Share to Carcinoma, Renal Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Cell Movement

Share to Cell Proliferation

Share to Gene Expression Regulation, Neoplastic

Share to Kidney Neoplasms

Share to MicroRNAs

Source

Open in PubMed Open full text

Identifiers

PMID: 30082525
DOI: 10.4103/0366-6999.238153
PMCID: PMC6085851

Genes

YWHAZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-375 Suppresses the Tumor Aggressive Phenotypes of Clear Cell Renal Cell Carcinomas through Regulating YWHAZ.PMID 30082525Read ↗

Molecular Mechanisms in Clear Cell Renal Cell Carcinoma: Role of miRNAs and Hypermethylated miRNA Genes in Crucial Oncogenic Pathways and ProcessesSemantic proximity Read ↗

miR-377 functions as a tumor suppressor in human clear cell renal cell carcinoma by targeting ETS1Semantic proximity Read ↗

MicroRNA-375: potential cancer suppressor and therapeutic drugSemantic proximity Read ↗

Targeting miRNAs in renal cell carcinoma: emerging therapeutic strategiesSemantic proximity Read ↗

Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

A Zic2/Runx2/NOLC1 signaling axis mediates tumor growth and metastasis in clear cell renal cell carcinomaSemantic proximity Read ↗

miRNA-target network reveals miR-124as a key miRNA contributing to clear cell renal cell carcinoma aggressive behaviour by targeting CAV1 and FLOT1Semantic proximity Read ↗

Oncogenic MicroRNAs Characterization in Clear Cell Renal Cell CarcinomaSemantic proximity Read ↗

MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAsSemantic proximity Read ↗

MiR-765 functions as a tumour suppressor and eliminates lipids in clear cell renal cell carcinoma by downregulating PLP2Semantic proximity Read ↗

The emerging role of miR‐375 in cancerSemantic proximity Read ↗

miR-93-3p inhibition suppresses clear cell renal cell carcinoma proliferation, metastasis and invasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.