Article

Integrated single cell functional-proteomic profiling of human skeletal muscle reveals a shift in cellular specificity in nemaline myopathy

2024-10-17

Abstract excerpt

Skeletal muscle is a complex syncytial arrangement of an array of cell types and, in the case of muscle specific cells (myofibers), sub-types. There exists extensive heterogeneity in skeletal muscle functional behaviour and molecular landscape, at the cell composition, myofiber sub-type and intra-myofiber sub-type level. This heterogeneity highlights limitations in currently applied methodological approaches, whic...

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Literature Corpus work: 1dbcf8c0-b05b-551c-a92b-f7feb6782c8e
DOI: 10.1101/2024.10.17.618209

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