Article

AptaBLE: A Deep Learning Platform for Aptamer Generation and Analysis

2026-01-07

Abstract excerpt

Aptamers are single-stranded oligonucleotides that bind molecular targets with high affinity and specificity. However, their discovery remains time-consuming, expensive, and susceptible to experimental biases. Here we present AptaBLE, a deep learning framework for predicting aptamer-protein binding. Additionally, we demonstrate two de novo generation methods that produce novel aptamers with desired specificity pr...

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Literature Corpus work: 1d966aec-f2a9-5af1-b627-95fef0d108e5
DOI: 10.64898/2026.01.06.698056

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