Article

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s disease

2023-01-27

Abstract excerpt

<title>Abstract</title> <p>While numerous single nucleotide variants and small indels have been identified in Parkinson’s disease (PD), the genome-wide contribution of structural variants (SVs), copy number variants (CNVs) and short tandem repeats (STRs) remains poorly understood. Here we investigated the association between these variants and PD using the high-depth whole-genome sequencing data from 466 PD patie...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1d5afb5b-71cc-56b8-96fe-e55ec73db345
DOI: 10.21203/rs.3.rs-2409337/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s diseaseDOI 10.21203/rs.3.rs-2409337/v1Read

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s diseaseSemantic proximity Read

Genome-wide association study of copy number variations in Parkinson’s diseaseSemantic proximity Read

Genome-wide contribution of common Short-Tandem Repeats to Parkinson’s Disease genetic riskSemantic proximity Read

Genome-wide analysis of Structural Variants in Parkinson’s Disease using Short-Read Sequencing dataSemantic proximity Read

High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts.Semantic proximity Read

Genome-wide contribution of common short-tandem repeats to Parkinson's disease genetic risk.Semantic proximity Read

Copy number variability in Parkinson's disease: assembling the puzzle through a systems biology approach.Semantic proximity Read

Genome-Wide Analysis of Structural Variants in Parkinson Disease.Semantic proximity Read

Repeat expansions in Parkinson’s disease and parkinsonism across ancestries: insights from a global genetic cohortSemantic proximity Read

Complementarity of long-read sequencing and optical genome mapping in Parkinson’s diseaseSemantic proximity Read

Structural genomic variations and Parkinson's disease.Semantic proximity Read

Long-read sequencing resolves a complex structural variant in<i>PRKN</i>Parkinson’s diseaseSemantic proximity Read