Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Copy number variability in Parkinson's disease: assembling the puzzle through a systems biology approach.

Human genetics - 1 Jan 2017

La Cognata Valentina, Morello Giovanna, D'Agata Velia, Cavallaro Sebastiano

Abstract excerpt

Parkinson's disease (PD), the second most common progressive neurodegenerative disorder of aging, was long believed to be a non-genetic sporadic origin syndrome. The proof that several genetic loci are responsible for rare Mendelian forms has represented a revolutionary breakthrough, enabling to reveal molecular mechanisms underlying this debilitating still incurable condition. While single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to Chromosome Deletion
Share to DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Parkinson Disease

Share to Protein Deglycase DJ-1

Share to Proton-Translocating ATPases

Share to Systems Biology

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 27896429
DOI: 10.1007/s00439-016-1749-4
PMCID: PMC5214768

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Copy number variability in Parkinson's disease: assembling the puzzle through a systems biology approach.PMID 27896429Read ↗

Genome-wide association study of copy number variations in Parkinson’s diseaseSemantic proximity Read ↗

High-resolution arrays reveal burden of copy number variations on Parkinson disease genes associated with increased disease risk in random cohorts.Semantic proximity Read ↗

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s diseaseSemantic proximity Read ↗

Copy Number Variations in Amyotrophic Lateral Sclerosis: Piecing the Mosaic Tiles Together through a Systems Biology Approach.Semantic proximity Read ↗

High-depth whole-genome sequencing identifies structure variants, copy number variants and short tandem repeats associated with Parkinson’s diseaseSemantic proximity Read ↗

Genetic landscape of Parkinson’s disease and related diseases in LuxembourgSemantic proximity Read ↗

Genome-wide Analysis of Copy Number Variation in Latin American Parkinson's Disease PatientsSemantic proximity Read ↗

A comprehensive analysis of deletions, multiplications, and copy number variations in PARK2.Semantic proximity Read ↗

Integrated Sequencing & Array Comparative Genomic Hybridization in Familial Parkinson’s DiseaseSemantic proximity Read ↗

Copy number variation in familial Parkinson disease.Semantic proximity Read ↗

Comprehensive genetic screening of the South African Parkinson’s disease study collection using the NeuroBooster arraySemantic proximity Read ↗

Targeted copy number variant identification across the neurodegenerative disease spectrum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.