Article

CIS deletion by CRISPR/Cas9 enhances human primary natural killer cell functions against allogeneic glioblastoma

2023-04-27

Abstract excerpt

<title>Abstract</title> <p>Glioblastoma (GBM) is the most common malignant brain tumor and has “immunologically cold” features. Changing GBM to an “immunologically hot” tumor requires a strong trigger that induces initial immune responses in GBM. Allogeneic natural killer cells (NKCs) have gained considerable attention as promising immunotherapeutic tools against cancer, where gene-edited NKCs would result in eff...

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Literature Corpus work: 1cede807-9ec4-54dc-ab4b-070c7c8f5a21
DOI: 10.21203/rs.3.rs-2839998/v1

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