Article

Exploring Biomarkers Related to Autophagy in Alzheimer's Disease Based on Pathway Crosstalk Analysis

2021-08-10

Abstract excerpt

<title>Abstract</title> <p>The pathological mechanism of Alzheimer's disease (AD) involves multiple pathways, and the crosstalk between autophagy and other pathways plays an increasingly prominent role in AD. However, current methods are primarily based on single-gene analysis or a single signal pathway to find therapeutic targets for AD, which are somewhat limited. The aim of our study is to identify autophagy-r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1cb02bc9-1797-5c0e-840d-725fe9947258
DOI: 10.21203/rs.3.rs-784797/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring Biomarkers Related to Autophagy in Alzheimer's Disease Based on Pathway Crosstalk AnalysisDOI 10.21203/rs.3.rs-784797/v1Read

Investigation of the potential connections between NAFLD-associated Alzheimer's disease: bioinformatics analysis of shared genesSemantic proximity Read

Identifying and Ranking Potential Driver Genes of Alzheimer's Disease Using Weighted Co-Expression Network AnalysisSemantic proximity Read

Gene biomarker discovery at different stages of Alzheimer using gene co-expression network approachSemantic proximity Read

Uncovering neuroinflammation-related modules and potential repurposing drugs for Alzheimer's disease through multi-omics data integrative analysisSemantic proximity Read

Identifying dysfunctional crosstalk of pathways in various regions of Alzheimer's disease brainsSemantic proximity Read

Identification of Autophagy-Related Biomarkers and Diagnostic Model in Alzheimer’s DiseaseSemantic proximity Read

Application of Weighted Gene Co-Expression Network Analysis to Explore the Key Genes in Alzheimer's Disease.Semantic proximity Read

Deciphering lysosomal autophagy-linked differential gene signatures in Alzheimer’s disease: Multicohort bioinformatics analysis leveraging Gene Expression Omnibus datasetsSemantic proximity Read

Weighted Gene Co-expression Network Analysis Identifies Specific Modules and Hub Genes Related to Alzheimer's DiseaseSemantic proximity Read

Integrated Analysis of Genes Related to Alzheimer’s Disease Pathogenesis Using Gene Co-expression NetworksSemantic proximity Read

Candidate Genes and MiRNAs Linked to the Inverse Relationship Between Cancer and Alzheimer’s Disease: Insights From Data Mining and Enrichment AnalysisSemantic proximity Read

Identification of Genetic Markers and Immune Infiltration Characteristics of Alzheimer’s Disease Through Weighted Gene Co-expression Network AnalysisSemantic proximity Read