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Enhanced K <sub>Na</sub> 1.1 Channel Underlies Cortical Hyperexcitability and Seizure Susceptibility after Traumatic Brain Injury

2023-10-17

Abstract excerpt

Pathogenic variants of the sodium-activated potassium channel K Na 1.1, have been reported in multiple epileptic disorders. However, whether and how K Na 1.1 channel is involved in epileptogenesis after traumatic brain injury (TBI) remains unknown. Firstly, we used behavioral monitoring and EEG recording to examine physiological property, spontaneous seizure activity, and seizure susceptibility after TBI. We exp...

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Literature Corpus work
1c3f33c8-25fc-53d9-a9f6-2bb836e1a138
DOI
10.1101/2023.10.14.562359
Open publication

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Enhanced K <sub>Na</sub> 1.1 Channel Underlies Cortical Hyperexcitability and Seizure Susceptibility after Traumatic Brain InjuryDOI 10.1101/2023.10.14.562359
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