Article

A novel human enteroid-anaerobe co-culture system to study microbial-host interaction under physiological hypoxia

2019-02-20

Abstract excerpt

Mechanistic investigations of host-microbe interactions in the human gut are limited by current co-culture model systems. The intestinal epithelium requires oxygen for viability, while gut bacteria are facultative or obligate anaerobes. The ability to model host-commensal interactions under dynamic oxygen conditions is critical to understanding host-pathogen interactions in the human gut. Here, we demonstrate a si...

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Literature Corpus work: 1b5e5706-f0ba-52bd-9b82-13a1c8ff5a82
DOI: 10.1101/555755

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