Article

Benchmark for simple and complex genome inversions

2025-12-01

Abstract excerpt

<h4>Background: </h4> Inversions represent a consequential yet under-characterized form of structural variation, with roles in genomic disorders, evolution, and genome instability. However, their detection remains technically challenging, particularly within repeat-dense regions and for complex multi-breakpoint events. A lack of dedicated, high-quality benchmarks has hindered algorithmic improvement, performance c...

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Literature Corpus work: 1b4dd81b-f3e0-5cee-a994-f044682497eb
DOI: 10.1101/2025.11.28.691176

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