InvertypeR: Bayesian inversion genotyping with Strand-seq data.

Abstract excerpt

BACKGROUND: Single cell Strand-seq is a unique tool for the discovery and phasing of genomic inversions. Conventional methods to discover inversions with Strand-seq data are blind to known inversion locations, limiting their statistical power for the detection of inversions smaller than 10 Kb. Moreover, the methods rely on manual inspection to separate false and true positives. RESULTS: Here we describe...

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