Article

New insights about myofibrillar myopathies: the role of metalloproteinases 2 and 9 in the pathogenesis

2020-04-03

Abstract excerpt

<title>Abstract</title> <p>Background There are few reports suggesting that gene expression and activation of various matrix metalloproteinases (MMPs) are deregulated. MMP-2 and MMP-9 represent the two MMPs, which degrade type IV collagen, the component of basement membrane. Methods We analyzed the involvement of gelatinases, MMP-2 and MMP-9, in the pathogenesis of myofibrillar myopathy (MFM). Muscle specimens...

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Literature Corpus work: 1b1f57c9-e28b-536c-9998-1de6181b0a61
DOI: 10.21203/rs.2.20954/v2

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