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Article

Active matrix metalloprotease-9 is associated with the collagen capsule surrounding the Madurella mycetomatis grain in mycetoma.

PLoS neglected tropical diseases - 1 Mar 2014

Geneugelijk Kirsten, Kloezen Wendy, Fahal Ahmed H, van de Sande Wendy W J

Abstract excerpt

Madurella mycetomatis is the main causative organism of eumycetoma, a persistent, progressive granulomatous infection. After subcutaneous inoculation M. mycetomatis organizes itself in grains inside a granuloma with excessive collagen accumulation surrounding it. This could be contributing to treatment failure towards currently used antifungal agents. Due to their pivotal role in tissue remodelling, matrix...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24675764
DOI: 10.1371/journal.pntd.0002754
PMCID: PMC3967957

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