Article

Autophagic stress activates distinct compensatory secretory pathways in neurons

2024-11-07

Abstract excerpt

<h4>ABSTRACT</h4> Autophagic dysfunction is a hallmark of neurodegenerative disease, leaving neurons vulnerable to the accumulation of damaged organelles and proteins. However, the late onset of diseases suggests that compensatory quality control mechanisms may be engaged to delay the deleterious effects induced by compromised autophagy. Neurons expressing common familial Parkinson’s disease (PD)-associated mutat...

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Literature Corpus work: 1ab34eb7-85cb-5321-bed9-d9083db06755
DOI: 10.1101/2024.11.07.621551

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