Article

Biliatresone treatment of pregnant mice causes changes in bile metabolism and liver inflammation in their offspring

2023-03-03

Abstract excerpt

<h4>Background & Aims</h4> Biliary atresia is a neonatal disease characterized by bile duct and liver damage, fibrosis, inflammation and abnormal bile metabolism. It appears to result from a prenatal exposure that spares the mother and affects the fetus. Our aim was to define the phenotype in neonatal mice after maternal exposure to low-dose biliatresone, a plant toxin implicated in biliary atresia in livestock....

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Literature Corpus work: 1a9f4298-0259-5a17-8235-e18a978156c8
DOI: 10.1101/2023.03.02.530913

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