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Maternal prenatal stress and its neuropsychological sequelae in infants and mother–infant dyadic quality: A systematic review and meta-analysis protocol

2026-06-17

Abstract excerpt

<h4>Background: </h4> Prenatal maternal stress represents a significant public health concern within the Developmental Origins of Health and Disease (DOHaD) framework. Unlike transient adaptive stress, chronic prenatal stress triggers sustained hypothalamic–pituitary–adrenal (HPA) axis dysregulation, elevating maternal glucocorticoid levels and enabling cortisol transfer across the placenta. Reduced placental 11β-...

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Literature Corpus work
1a8d14f9-61e5-5ecb-8aff-aa094254faa0
DOI
10.12688/openreseurope.23717.1
Open publication

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Maternal prenatal stress and its neuropsychological sequelae in infants and mother–infant dyadic quality: A systematic review and meta-analysis protocolDOI 10.12688/openreseurope.23717.1
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