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Comparative Efficacy and Safety of Pharmacological Prophylactic Agents for Migraine in Children and Adolescents: A Systematic Review and Bayesian Network Meta-Analysis

2026-08-03

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<title>Abstract</title> <p> Background Migraine is a leading cause of recurrent disabling headache in children and adolescents, yet most prophylactic agents have failed to outperform placebo, and head-to-head trials are scarce. We conducted a network meta-analysis (NMA) comparing the efficacy and safety of pharmacological migraine prophylaxis in pediatric patients. Methods We searched PubMed, Cochrane CENTRAL,...

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Literature Corpus work
1a7a8e16-cbbf-56e1-959c-1909c21805ae
DOI
10.21203/rs.3.rs-10473364/v1
Open publication

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Comparative Efficacy and Safety of Pharmacological Prophylactic Agents for Migraine in Children and Adolescents: A Systematic Review and Bayesian Network Meta-AnalysisDOI 10.21203/rs.3.rs-10473364/v1
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